The EACR Image of the Month highlights both scientifically and visually stimulating cancer research images from EACR members.
Congratulations to Dr. Martin Barr of St. James’s Hospital & Trinity College Dublin in Ireland. June’s winning image depicts β-catenin protein expression and localization in lung cancer cells.
Winner: β-catenin protein expression and localization in lung cancer cells
A link between β-catenin and various cancer types has previously been described. In a cisplatin resistant model of NSCLC, H460 cells were examined for expression of β-catenin by immunofluorescence using primary anti-β-catenin and secondary Alexa Fluor® 488-labelled antibodies. Cells were analysed using the IN Cell Analyzer 1000 system. Cells showing green fluorescence are representative of β-catenin expression and localization while nuclear staining is shown in blue (Hoechst 33342) at ×40 magnification.
Submitted by: Dr. Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St. James’s Hospital & Trinity College Dublin, Ireland
05 Jun 2017