EACR Image of the Month: June 2017 | St. James's Hospital Foundation EACR Image of the Month: June 2017 | St. James's Hospital Foundation

EACR Image of the Month: June 2017

The EACR Image of the Month highlights both scientifically and visually stimulating cancer research images from EACR members.

 

Congratulations to Dr. Martin Barr of St. James’s Hospital & Trinity College Dublin in Ireland.  June’s winning image depicts β-catenin protein expression and localization in lung cancer cells.

 

Winner: β-catenin protein expression and localization in lung cancer cells

 

A link between β-catenin and various cancer types has previously been described. In a cisplatin resistant model of NSCLC, H460 cells were examined for expression of β-catenin by immunofluorescence using primary anti-β-catenin and secondary Alexa Fluor® 488-labelled antibodies. Cells were analysed using the IN Cell Analyzer 1000 system. Cells showing green fluorescence are representative of β-catenin expression and localization while nuclear staining is shown in blue (Hoechst 33342) at ×40 magnification.

 

Submitted by: Dr. Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St. James’s Hospital & Trinity College Dublin, Ireland

 

05 Jun 2017

 

 

 

image depicts β-catenin protein expression and localization in lung cancer cells.